This documentation is split into 11 parts:

Overview of the Immune System – Purpose, general structure, innate vs adaptive summary, systemic organization.
Immune Organs & Tissues – Bone marrow, thymus, lymph nodes, spleen, MALT, microenvironments, primary vs secondary vs tertiary structures.
Innate Immunity – Barriers (skin, mucosa), phagocytes (macrophages, neutrophils, dendritic cells), NK cells, complement pathways, pattern recognition receptors, inflammasomes, inflammatory response.

- Adaptive Immunity – B cells, T cells (helper, cytotoxic, regulatory, memory), antibodies, antigen presentation (MHC I/II), clonal selection, immunological memory, class switching, somatic hypermutation.

Molecular Mediators & Signaling – Cytokines, chemokines, transcription factors, signaling pathways (NF-κB, JAK-STAT, MAPK, PI3K), growth factors, receptors.
Immune Responses to Pathogens – Responses to bacteria, viruses, fungi, parasites; immune evasion strategies; microbiome interactions.
Inflammation & Immune Regulation – Acute vs chronic inflammation, resolution mechanisms, immune checkpoints, tolerance, regulatory cells.
Immunopathology & Disorders – Autoimmunity, immunodeficiencies (primary, secondary), allergies/hypersensitivities, chronic inflammation, transplant rejection, graft-vs-host disease.
Vaccination & Immunotherapy – Principles, vaccine types, monoclonal antibodies, CAR-T, checkpoint inhibitors, cytokine therapies.
Development & Aging – Fetal and neonatal immunity, thymic involution, immunosenescence.
Systems Integration – Neuroimmune interactions, endocrine-immune crosstalk, circadian regulation, metabolism-immune links.

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